drugset / Trial / NCT03454984

SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantation

NCT03454984

Phase 2 Unknown 40 enrolled Groupe Francophone des Myelodysplasies
NaSingle-groupOpen-labelPrevention

Summary

High risk MDS (Myelodysplastic Syndrome) patients will be treated with SGI-110 after Allogeneic Stem Cell Transplantation in the hypothesis that SGI-110 maintenance given early after HSCT can prevent relapse without increasing non-relapse mortality translating in an improved disease-free survival.

Timeline

Start
2018-11
Primary completion
2020-09
Completion
2022-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Guadecitabine Oligonucleotide (other) 30 unknown Subcutaneous