drugset / Trial / NCT03461406

A Study of Safety and Efficacy of Fibrin Sealant Grifols as an Adjunct to Haemostasis During Surgery in Paediatric Participants

NCT03461406

Phase 3 Completed 186 enrolled Grifols, S.A.
RandomizedParallel-groupSingle-blindTreatment

Summary

The objective of the study is to evaluate if FS Grifols is non-inferior to EVICEL® in terms of the percentage of participants achieving hemostasis at the target bleeding site (TBS) by 4 minutes (T4) from the start of treatment application (TStart) with no occurrence of rebleeding until the completion of the surgical closure by layers of the exposed surgical field containing the TBS (TClosure).

Timeline

Start
2019-01-18
Primary completion
2022-04-15
Completion
2022-05-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Fibrin Sealant Grifols Protein / enzyme biologic 80 mg/ml Topical
Subject Fibrin Sealant Grifols Protein / enzyme biologic 500 iu Topical
Comparator Fibrinogen Concentrate Human Protein / enzyme biologic Topical

Indications

No indication recorded.