drugset / Trial / NCT03463525

Open-label PET Study With [11C]Osimertinib in Patients With EGFRm NSCLC and Brain Metastases

NCT03463525

Phase 1 Completed 4 enrolled AstraZeneca
NaSingle-groupOpen-labelOther

Summary

This is an open-label, single centre, Phase I study to determine the brain exposure of \[11C\]osimertinib in patients with EGFRm NSCLC with brain metastases.

Timeline

Start
2018-10-24
Primary completion
2020-03-19
Completion
2020-10-05

Drugs

EvaluationDrugModalityDoseRoute
Subject [11C]osimertinib Unknown Intravenous
Background Osimertinib Small molecule 80 mg Oral