Duloxetine for Acute Post-mastectomy Pain

Completed 88 enrolled Assiut University

RandomizedParallel-groupDouble-blindTreatment

Summary

The objective of this study is to evaluate the analgesic effect of oral dulexitine tablet (administered 2 h before surgery) as well as the ideal dose for acute postmastectomy pain.

Timeline

Start: 2018-04-01
Primary completion: 2020-02-10
Completion: 2020-02-10

Publications

Hetta DF, Elgalaly NA, Hetta HF, Fattah Mohammad MA. Preoperative Duloxetine to improve acute pain and quality of recovery in patients undergoing modified radical mastectomy: A dose-ranging randomized controlled trial. J Clin Anesth. 2020 Dec;67:110007. doi: 10.1016/j.jclinane.2020.110007. Epub 2020 Aug 22.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Duloxetine	Small molecule	30 mg	Oral
Comparator	Duloxetine	Small molecule	60 mg	Oral
Comparator	Duloxetine	Small molecule	90 mg	Oral

Indications

No indication recorded.