drugset / Trial / NCT03469934

Proof of Concept Study to Investigate Etokimab (ANB020) Activity in Adult Participants With Severe Eosinophilic Asthma

NCT03469934

Phase 2 Completed 25 enrolled AnaptysBio, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a proof of concept study designed to assess the effects of a single intravenous dose of etokimab compared to placebo in adult participants with severe eosinophilic asthma. This study will also assess the safety and tolerability of etokimab in adult participants with severe eosinophilic asthma.

Timeline

Start
2017-11-14
Primary completion
2018-10-30
Completion
2018-10-30

Publications

  • Results Pavord ID, Marquette A, Kahm P, Pinkstaff J, Sacco N, Londei M. Single-dose Phase 2a trial of etokimab (anti-IL-33) in severe eosinophilic asthma. Paper presented at the European Academy of Allergy and Clinical Immunology (EEACI) Congress 2019; June 1-5, 2019; Lisbon, Portugal.

Drugs

EvaluationDrugModalityDoseRoute
Subject Etokimab Monoclonal antibody 300 mg Intravenous

Indications

No indication recorded.