Interaction Between NGF and Acute Exercise-induced Ischemia

Phase 0 Completed 21 enrolled Aalborg University

RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of this study is to investigate pain evoked responses and facilitation of NGF-induced mechanical muscle hyperalgesia over time following an acute exercised-induced ischemic condition in a NGF-sensitized muscle.

Timeline

Start: 2018-03-15
Primary completion: 2018-05-15
Completion: 2018-06-15

Publications

Sorensen LB, Gazerani P, Graven-Nielsen T. Nerve growth factor-induced muscle hyperalgesia facilitates ischaemic contraction-evoked pain. Eur J Pain. 2019 Nov;23(10):1814-1825. doi: 10.1002/ejp.1455. Epub 2019 Aug 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	nerve growth factor	Cell therapy	1 ug	Intramuscular

Indications

No indication recorded.