Effects of THC on Emotional Memory Retrieval

Phase 0 Completed 24 enrolled University of Chicago

RandomizedCrossoverDouble-blindBasic science

Summary

The main purpose of this study was to examine the effects of THC on the retrieval of emotional and neutral memories in healthy young adults. Secondary experiments included the effects of THC on the encoding of object and scene stimuli and a novel working memory task.

Timeline

Start: 2017-02-15
Primary completion: 2017-10-04
Completion: 2017-10-04

Publications

Doss MK, Weafer J, Gallo DA, de Wit H. Delta9-Tetrahydrocannabinol During Encoding Impairs Perceptual Details yet Spares Context Effects on Episodic Memory. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Jan;5(1):110-118. doi: 10.1016/j.bpsc.2019.08.007. Epub 2019 Aug 30.
Doss MK, Weafer J, Gallo DA, de Wit H. Delta9-Tetrahydrocannabinol at Retrieval Drives False Recollection of Neutral and Emotional Memories. Biol Psychiatry. 2018 Nov 15;84(10):743-750. doi: 10.1016/j.biopsych.2018.04.020. Epub 2018 May 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Δ9-tetrahydrocannabinol	Unknown	15 mg	Oral

Indications

No indication recorded.