drugset / Trial / NCT03480438

Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab

NCT03480438

Phase 2 Completed 52 enrolled Goethe University
NaSingle-groupOpen-labelTreatment

Summary

The trial proposed here attempts to reduce induction chemotherapy to phase I of standard induction in patients with B-precursor ALL. Induction phase II will be replaced by blinatumomab. The initial treatment phase is followed by sequential chemotherapy and further blinatumomab cycles.

Timeline

Start
2018-06-01
Primary completion
2024-01-10
Completion
2024-01-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Blinatumomab Monoclonal antibody 9 ug Intravenous
Subject Blinatumomab Monoclonal antibody 28 ug Intravenous