drugset / Trial / NCT03486236

A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects

NCT03486236 ↗

Phase 1 Completed 16 enrolled Vertex Pharmaceuticals Incorporated
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study evaluated the safety and pharmacokinetics of multiple ascending doses of VX-440 in combination with tezacaftor/ivacaftor (TEZ/IVA) (triple combination \[TC\]) administered for 13 days to healthy male and female subjects

Timeline

Start
2016-07-20
Primary completion
2016-09-14
Completion
2016-09-14

Drugs

EvaluationDrugModalityDoseRoute
Subject IVA Unknown — —
Subject OLACAFTOR Small molecule — —
Subject TEZ Unknown — —

Indications