drugset / Trial / NCT03498300

Seroprevalence of Bordetella Pertussis Antibodies and Anti-pertussis Antibody Response After a Single Dose of Tdap in Pregnant Thai Women

NCT03498300

Phase 0 Completed 129 enrolled Mahidol University
RandomizedParallel-groupOpen-labelPrevention

Summary

This study evaluated the seroprevalence of Bordetella pertussis antibodies and anti-pertussis antibody response after a single dose of reduced-antigen, combined diphtheria, tetanus, and acellular pertussis vaccine (Tdap) in pregnant Thai women. All seronegative participants received Tdap, while seropositive participants were equally randomized into 2 groups. Half of seropositive participants received Tdap and the other half received tetanus-diphtheria (Td) as standard protocol.

Timeline

Start
2018-05-09
Primary completion
2019-04-13
Completion
2019-04-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Adacel Vaccine