drugset / Trial / NCT03498456

Triple Therapy With Tegoprazan in H. Pylori Positive Patients

NCT03498456

Phase 3 Completed 284 enrolled HK inno.N Corporation
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The current study is designed to demonstrate the non-inferiority of tegoprazan triple therapy (tegoprazan, amoxicillin, and clarithromycin; hereinafter TAC) to lansoprazole triple therapy (lansoprazole, amoxicillin, and clarithromycin; hereinafter LAC) in terms of H. pylori eradication rate and to evaluate the safety of tegoprazan after oral administration of the therapy for 7 days, twice daily in H. pylori positive patients.

Timeline

Start
2018-06-28
Primary completion
2019-12-31
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lansoprazole Other / unclassified 30 mg Oral
Subject Tegoprazan Other / unclassified 50 mg Oral
Comparator Amoxicillin Other / unclassified 1000 mg Oral
Comparator Clarithromycin Small molecule 500 mg Oral