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drugset / Trial / NCT03499106

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

NCT03499106 ↗

Phase 1 Completed 24 enrolled Cyclerion Therapeutics
NaSingle-groupOpen-labelOther

Summary

The primary objective of the study is to evaluate the effect of itraconazole (a potent cytochrome P450 isoenzyme \[CYP\]3A inhibitor) on the pharmacokinetics of IW-1973.

Timeline

Start
2018-04-12
Primary completion
2018-07-06
Completion
2018-07-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Itraconazole Small molecule — Oral
Subject Praliciguat Small molecule — Oral

Indications

No indication recorded.