drugset / Trial / NCT03500731
Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether a lung transplantation prior to bone marrow transplantation (BMT) would allow for restoration of pulmonary function prior to BMT, allowing to proceed to BMT, to restore hematologic function.
Timeline
- Start
- 2018-04-19
- Primary completion
- 2027-12
- Completion
- 2028-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CD3/CD19 negative hematopoietic stem cells | Cell therapy | — | — |
| Background | Alemtuzumab | Monoclonal antibody | — | — |
| Background | Fludarabine | Small molecule | — | — |
| Background | G-CSF | Unknown | — | — |
| Background | Hydroxyurea | Other / unclassified | — | — |
| Background | Rituximab | Monoclonal antibody | — | — |
| Background | Thiotepa | Other / unclassified | — | — |