drugset
drugset / Trial / NCT03502967

Imaging of Traumatic Brain Injury Metabolism Using Hyperpolarized Carbon-13 Pyruvate

NCT03502967 ↗

Phase 0 Enrolling by invitation 60 enrolled University of Texas Southwestern Medical Center
Non-randomizedParallel-groupOpen-labelBasic science

Summary

This project is to evaluate sensitivity and specificity of hyperpolarized 13C-pyruvate as imaging agents of altered cerebral glycolysis and mitochondrial dysfunction and assess pyruvate utilization in mitochondria in Traumatic Brain Injury (TBI) patients.

Timeline

Start
2018-06-01
Primary completion
2026-06-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Hyperpolarized [1-13C] Pyruvate Diagnostic / imaging agent — Other
Subject Hyperpolarized [2-13C] Pyruvate Diagnostic / imaging agent — Other

Indications

traumatic brain injury