drugset / Trial / NCT03503331
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
Phase 2
Recruiting
160 enrolled
University of Alabama at Birmingham
National Institute on Aging (NIA) · collab
NaSingle-groupOpen-labelDiagnostic
Summary
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer \[C-11\]PiB in participants in the UAB Alzheimer's Disease Center cohort. Assessment of interactions between race and vascular risk factors, brain amyloid levels measured with \[C-11\]PiB-PET, and cognitive status will be the primary outcome of this imaging study.
Timeline
- Start
- 2018-04-20
- Primary completion
- 2028-10
- Completion
- 2028-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | C-11 PiB | Diagnostic / imaging agent | 300 mbq | Intravenous |
| Subject | C-11 PiB | Diagnostic / imaging agent | 670 mbq | Intravenous |