drugset / Trial / NCT03508726

High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas

NCT03508726

Phase 1/2 Completed 25 enrolled Mohammed Milhem University of Iowa · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a single-arm open-label phase Ib/II clinical study assessing the efficacy of concurrent high dose ascorbate in combination with radiotherapy in patients with locally advanced, resectable, high grade sarcomas.

Timeline

Start
2019-06-27
Primary completion
2022-06-03
Completion
2024-06-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Vitamin C Other / unclassified 62.5 g Intravenous
Subject Vitamin C Other / unclassified 75 g Intravenous

Indications