drugset / Trial / NCT03514719
PD-L1 Imaging in Non Small Cell Lung Cancer' (PINNACLE)
Phase 1
Completed
24 enrolled
Radboud University Medical Center
Merck KGaA, Darmstadt, Germany · collab
NaSingle-groupOpen-labelDiagnostic
Summary
In this feasibility study, a zirconium-89 (89Zr)-avelumab positron emission tomography (PET) scan will be performed in 37 patients prior to treatment with avelumab to: 1. assess the tumor and systemic tissue uptake 89Zr-avelumab 2. assess the potential to predict avelumab treatment response
Timeline
- Start
- 2018-10-01
- Primary completion
- 2021-09-15
- Completion
- 2021-12-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avelumab | Monoclonal antibody | 10 mg/kg | Intravenous |