drugset / Trial / NCT03515824
Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the safety and preliminary efficacy of MK-1697. There are 2 parts in this study: dose escalation to determine the recommended phase 2 dose (RP2D) and confirm the RP2D (Part A) and cohort expansion to determine preliminary efficacy in participants with colorectal cancer (CRC) or head and neck squamous cell cancer (HNSCC) (Part B). No formal hypothesis testing will be done in this study.
Timeline
- Start
- 2018-08-13
- Primary completion
- 2020-02-18
- Completion
- 2020-02-18
Outcome
Outcome not reported
Stopped (Business): “Business Reasons”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MK-1697 | Unknown | 20 mg | Intravenous |
| Subject | MK-1697 | Unknown | 65 mg | Intravenous |
| Subject | MK-1697 | Unknown | 200 mg | Intravenous |