drugset / Trial / NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
NaSequentialOpen-labelTreatment
Summary
This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and immunogenicity, and to preliminarily assess anti-tumor activity of XmAb20717 in subjects with selected advanced solid tumors.
Timeline
- Start
- 2018-07-10
- Primary completion
- 2022-06-01
- Completion
- 2022-09-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Vudalimab | Monoclonal antibody | — | Intravenous |
Indications
anal squamous cell carcinoma
basal cell carcinoma
breast carcinoma
cervical cancer
cholangiocarcinoma
endometrial carcinoma
fallopian tube carcinoma
head and neck squamous cell carcinoma
hepatocellular carcinoma
melanoma
mesothelioma
nasopharyngeal carcinoma
non-small cell lung carcinoma
ovarian carcinoma
prostate carcinoma
renal cell carcinoma
salivary gland carcinoma
small cell lung carcinoma
squamous cell carcinoma of penis
thymic carcinoma
thymoma
urothelial carcinoma
uterine adnexa cancer
vulvar carcinoma