drugset / Trial / NCT03521960
Buspirone for Opioid Tapering
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a pilot study to collect preliminary data to support a grant application. The goal of the study is to evaluate whether the Food and Drug Administration (FDA)-approved and generically-available medication buspirone reduces symptoms of opioid withdrawal among patients undergoing a clinically-indicated and supervised taper from their opioid pain medications. This is premised on strong preclinical scientific support but has not yet be well-examined in humans.
Timeline
- Start
- 2018-05-30
- Primary completion
- 2020-06-30
- Completion
- 2020-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Buspirone | Small molecule | 15 mg | Oral |