drugset / Trial / NCT03522142

A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies

NCT03522142

Phase 1 Terminated 83 enrolled Incyte Corporation
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and early clinical activity of single-agent INCB081776 (Part 1) and INCB081776 in combination with INCMGA00012 (Part 2).

Timeline

Start
2018-08-27
Primary completion
2025-09-10
Completion
2025-09-10

Drugs

EvaluationDrugModalityDoseRoute
Subject INCB081776 Unknown Oral
Subject Retifanlimab Monoclonal antibody 500 mg Intravenous

Indications