drugset / Trial / NCT03522207

Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient

NCT03522207

Phase 4 Terminated 3 enrolled University of Montreal Hospital Centre (CHUM)
RandomizedCrossoverDouble-blindTreatment

Summary

The objective is to evaluate the accuracy and efficacity of 1 dose of trazodone in TMD patient (with chronic orofacial pain and poor sleep quality). Subject will have 3 polysomnography (PSG) over 3 weeks. The first one being the baseline. Half of the patient will receive trazodone on their 2nd PSG and placebo on their 3rd PSG, and the other half will receive placebo bedofe their 2nd PSG and trazodone for the 3rd PSG. Pain quality and sleep quality will be assessed before and after PSG. polysomnograms from baseline, placebo night and trazodone night will also be compared.

Timeline

Start
2018-10-15
Primary completion
2020-01-20
Completion
2020-01-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Trazodone Small molecule 100 mg Oral