drugset / Trial / NCT03523767
Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of this pilot study is to investigate and compare the effect of a mild inflammatory stimulus (typhoid vaccine) on immune response, mood and cognition in healthy volunteers compared to patients with history Major Depressive Disorder (MDD) (not currently depressed and no symptoms of depression in the past 6 months).
Timeline
- Start
- 2018-02-07
- Primary completion
- 2020-02-07
- Completion
- 2020-02-07
Outcome
Outcome not reported
Stopped: “Early termination related to COVID pandemic”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | S.typhi | Vaccine | 0.5 ml | — |