drugset / Trial / NCT03523767

Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study

NCT03523767 ↗

RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of this pilot study is to investigate and compare the effect of a mild inflammatory stimulus (typhoid vaccine) on immune response, mood and cognition in healthy volunteers compared to patients with history Major Depressive Disorder (MDD) (not currently depressed and no symptoms of depression in the past 6 months).

Timeline

Start
2018-02-07
Primary completion
2020-02-07
Completion
2020-02-07

Outcome

Outcome not reported

Stopped: “Early termination related to COVID pandemic”

Drugs

EvaluationDrugModalityDoseRoute
Subject S.typhi Vaccine 0.5 ml —