drugset / Trial / NCT03524066
Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)
Completed
21 enrolled
Fraunhofer-Institute of Toxicology and Experimental Medicine
AstraZeneca · collab
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The aim of the present study is to increase the general understanding of lung PK of selected compounds by sampling epithelial lining fluid ELF and lung tissue.
Timeline
- Start
- 2018-04-10
- Primary completion
- 2018-12-31
- Completion
- 2018-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluticasone propionate | Other / unclassified | 500 ug | Inhaled |
| Subject | Propranolol | Small molecule | 40 mg | Oral |
| Subject | Salbutamol | Unknown | 200 ug | Inhaled |
| Subject | Salbutamol | Unknown | 8 mg | Inhaled |
| Subject | Salmeterol | Other / unclassified | 50 ug | Inhaled |
Indications
No indication recorded.