drugset / Trial / NCT03528564

Hemoglobin Optimization to Prevent Transfusion and Adverse Events in Perioperative Patients With Iron Restricted Anemia

NCT03528564

Phase 2 Terminated 4 enrolled Unity Health Toronto
RandomizedParallel-groupDouble-blindTreatment

Summary

The HOPE-Hb trial is a phase II study to determine the feasibility and impact of a combination treatment (intravenous iron plus erythropoietin) versus intravenous iron treatment alone on preoperative hemoglobin concentration before hip or knee arthroplasty.

Timeline

Start
2019-07-01
Primary completion
2021-05-31
Completion
2021-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Iron sucrose Unknown 900 mg Intravenous
Subject epoetin alfa Protein / enzyme biologic 40000 iu Subcutaneous