Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure

Completed 62 enrolled Mansoura University

RandomizedParallel-groupTriple-blindTreatment

Summary

This randomized trial aims to compare two topical treatments in the treatment of chronic anal fissure: minoxidil gel and glycreyl trintrate cream. The endpoint of the study is the duration of healing of anal fissure whereas secondary endpoints include adverse effects of each treatment and recurrence of anal fissure

Timeline

Start: 2018-05-10
Primary completion: 2019-08-30
Completion: 2019-09-30

Publications

Emile SH, Abdel-Razik MA, Elshobaky A, Elbaz SA, Khafagy W, Shalaby M. Topical 5% minoxidil versus topical 0.2% glyceryl trinitrate in treatment of chronic anal fissure: A randomized clinical trial. Int J Surg. 2020 Mar;75:152-158. doi: 10.1016/j.ijsu.2020.01.143. Epub 2020 Feb 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Minoxidil	Small molecule	5 %	Other
Comparator	Nitroglycerin	Unknown	0.2 %	Other

Indications

No indication recorded.