drugset / Trial / NCT03535480

Autologous Bone Marrow Stem Cell Ovarian Transplantation to Restore Ovarian Function in Premature Ovarian Failure

NCT03535480 ↗

Phase 4 Unknown 20 enrolled La Fe Health Research Institute
RandomizedParallel-groupSingle-blindTreatment

Summary

This study aims to recover ovarian function in POF/POI patients. With this pueprose we designed a study protocol including two arms: ASCOT arm, were patients receive the stem cell mobilization treatment with Granulocyte colony stimulating factor (G-CSF) followed by apheresis and ovarian artery catheterism to selectively infuse the stem cells into the ovary and the G-CSF arm including patients that receive the mobilization treatment but not the ovarian artery catheterism to selectively infuse the cells into the ovary.

Timeline

Start
2018-06
Primary completion
2020-06
Completion
2022-06

Drugs

EvaluationDrugModalityDoseRoute
Background G-CSF Unknown — Subcutaneous