D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain

Phase 2 Terminated 203 enrolled Northwestern University United States Department of Defense · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of D-cycloserine versus placebo in relieving the signs and symptoms of patients with chronic lower back pain.

Timeline

Start: 2018-03-30
Primary completion: 2024-02-07
Completion: 2024-02-07

Publications

Pinto CB, Bielefeld J, Barroso J, Yip B, Huang L, Schnitzer T, Apkarian AV. Chronic pain domains and their relationship to personality, abilities, and brain networks. Pain. 2023 Jan 1;164(1):59-71. doi: 10.1097/j.pain.0000000000002657. Epub 2022 Apr 20. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cycloserine	Small molecule	200 mg	—

Indications

No indication recorded.