drugset / Trial / NCT03541252

Topical Laser-assisted Combination Chemotherapy for Basal Cell Carcinoma- a Clinical Study

NCT03541252

Phase 1/2 Completed 20 enrolled Merete Haedersdal
NaSingle-groupOpen-labelTreatment

Summary

A prospective clinical, uncontrolled, open-label, explorative phase IIa trial on patients with histologically- confirmed superficial and nodular basal cell carcinoma (BCC) . The study assesses tolerability and tumor clearance after laser-assisted topical delivery of two synergistic chemotherapeutic agents, cisplatin and 5-fluorouracil (5-FU) in BCC patients.

Timeline

Start
2018-03-09
Primary completion
2019-09-02
Completion
2019-09-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 0.1 % Topical
Subject Cisplatin Other / unclassified 0.25 ml Topical
Subject fluorouracil Small molecule 0.125 ml Topical
Subject fluorouracil Small molecule 5 % Topical

Indications