drugset / Trial / NCT03542357
The Effect of Sumatriptan and Placebo on CGRP Induced Headache
RandomizedCrossoverDouble-blindTreatment
Summary
To develop a pragmatic migraine model the investigators will induce headache in healthy volunteers and in patients with migraine without aura with aCalcitonine Gene Related Peptide (CGRP). If the headache responds to sumatriptan, the model can be used to test new drug candidates.
Timeline
- Start
- 2018-02-15
- Primary completion
- 2018-09-01
- Completion
- 2018-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sumatriptan | Unknown | 50 mg | Oral |