drugset / Trial / NCT03553394

Effects of Restrictive Fluid Strategy on Postoperative Oliguric Pancreatic Surgery Patients

NCT03553394

Terminated 53 enrolled Uppsala University
RandomizedParallel-groupOpen-labelTreatment

Summary

Reduced urinary output is a common postoperative issue for patients going through major surgery such as pancreatic surgery. Commonly this is treated by increasing fluid administration to the patients and sometimes also diuretics. However, overloading patients with fluid also have several risks and known complications. Studies have also shown that a short period of decreased urinary output in the postoperative period do not have an increased incidence of acute renal failure. The aim of our study is to investigate the difference in renal function and postoperative complications associated with fluid overload on these patients that are randomized to either receiving a fluid bolus directly when urinary output decreases or to await for a maximum of four hours to see if urinary output increases spontaneously.

Timeline

Start
2018-10-01
Primary completion
2021-05-31
Completion
2022-08-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ringer acetate Other / unclassified 5 unknown Other

Indications