drugset / Trial / NCT03565536

Nexavar for Neoadjuvant Treatment of Anaplastic Thyroid Cancer

NCT03565536 ↗

Phase 2 Completed 18 enrolled Fujian Medical University
NaSingle-groupOpen-labelTreatment

Summary

Undifferentiated thyroid cancer is the most malignant tumor of the thyroid gland, with a median survival of only 3 months. Most undifferentiated cancers lose the chance of surgery when they are first diagnosed. The current study, Nexavar, is used only for dedifferentiated thyroid cancer and has not been applied to undifferentiated cancer. This study attempted to apply it to preoperative treatment of undifferentiated cancer to see if it would shrink the tumor and give the patient an opportunity for surgery.

Timeline

Start
2018-05-01
Primary completion
2020-12-30
Completion
2020-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 400 mg —