drugset / Trial / NCT03568071

A Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics (PK)/Pharmacodynamics (PD) of MOR106 in Subjects With Moderate to Severe Atopic Dermatitis

NCT03568071 ↗

Phase 2 Terminated 207 enrolled Lakefront Biotherapeutics NV
RandomizedSequentialQuadruple-blindTreatment

Summary

This is a Phase II, randomized, double-blind, placebo-controlled multicenter study of repeated doses of MOR106 administered as IV infusion. MOR106, is an antibody which is being developed as a treatment for diseases such as psoriasis and atopic dermatitis. An antibody is a protein that is made by the body in a defense reaction against viruses and bacteria or other small particles. In this case, MOR106 will act against IL-17C interleukin by binding to it. This way it could be possible to act against these diseases.

Timeline

Start
2018-04-26
Primary completion
2020-03-03
Completion
2020-03-03

Outcome

Outcome not reported

Stopped: “MOR106 clinical development in atopic dermatitis was stopped for futility”

Drugs

EvaluationDrugModalityDoseRoute
Subject MOR106 Monoclonal antibody — Intravenous

Indications