drugset / Trial / NCT03568071
A Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics (PK)/Pharmacodynamics (PD) of MOR106 in Subjects With Moderate to Severe Atopic Dermatitis
RandomizedSequentialQuadruple-blindTreatment
Summary
This is a Phase II, randomized, double-blind, placebo-controlled multicenter study of repeated doses of MOR106 administered as IV infusion. MOR106, is an antibody which is being developed as a treatment for diseases such as psoriasis and atopic dermatitis. An antibody is a protein that is made by the body in a defense reaction against viruses and bacteria or other small particles. In this case, MOR106 will act against IL-17C interleukin by binding to it. This way it could be possible to act against these diseases.
Timeline
- Start
- 2018-04-26
- Primary completion
- 2020-03-03
- Completion
- 2020-03-03
Outcome
Outcome not reported
Stopped: “MOR106 clinical development in atopic dermatitis was stopped for futility”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MOR106 | Monoclonal antibody | — | Intravenous |