drugset / Trial / NCT03573544
This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.
Non-randomizedSequentialOpen-labelTreatment
Summary
The purpose of this study is to establish the maximum tolerated dose (MTD) of OBI-888 as monotherapy. And to characterize the safety and preliminary clinical activity profile of the MTD dose of OBI-888 administered as monotherapy in patients with locally advanced or metastatic solid tumors.
Timeline
- Start
- 2018-05-07
- Primary completion
- 2022-04-07
- Completion
- 2022-04-07
Outcome
Outcome not reported
Stopped: “OBI-888 no longer fulfills our goal of developing cost-effective therapies for cancer patients”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | OBI-888 | Unknown | 5 mg/kg | Intravenous |
| Subject | OBI-888 | Unknown | 10 mg/kg | Intravenous |
| Subject | OBI-888 | Unknown | 20 mg/kg | Intravenous |