drugset / Trial / NCT03573544

This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.

NCT03573544 ↗

Phase 1/2 Terminated 54 enrolled OBI Pharma, Inc
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to establish the maximum tolerated dose (MTD) of OBI-888 as monotherapy. And to characterize the safety and preliminary clinical activity profile of the MTD dose of OBI-888 administered as monotherapy in patients with locally advanced or metastatic solid tumors.

Timeline

Start
2018-05-07
Primary completion
2022-04-07
Completion
2022-04-07

Outcome

Outcome not reported

Stopped: “OBI-888 no longer fulfills our goal of developing cost-effective therapies for cancer patients”

Drugs

EvaluationDrugModalityDoseRoute
Subject OBI-888 Unknown 5 mg/kg Intravenous
Subject OBI-888 Unknown 10 mg/kg Intravenous
Subject OBI-888 Unknown 20 mg/kg Intravenous

Indications