drugset / Trial / NCT03575403
Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
Phase 1
Completed
19 enrolled
Craig Rush
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedFactorialTriple-blindBasic science
Summary
This study will evaluate the behavioral effects of alcohol during maintenance on placebo, duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated human laboratory methods.
Timeline
- Start
- 2018-09-01
- Primary completion
- 2023-03-15
- Completion
- 2023-03-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Alcohol | Other / unclassified | — | — |
| Subject | Duloxetine | Small molecule | 30 mg | Oral |
| Subject | Duloxetine | Small molecule | 60 mg | Oral |
| Comparator | Methylphenidate | Small molecule | 0 mg | Oral |
| Comparator | Methylphenidate | Small molecule | 20 mg | Oral |
| Comparator | Methylphenidate | Small molecule | 40 mg | Oral |
| Comparator | Methylphenidate | Small molecule | 60 mg | Oral |