drugset / Trial / NCT03576807

The Clinical Research of Anti-CD20 CAR-T Cells in Patients With Refractory or Relapsed B Lymphocyte Lymphoma

NCT03576807

Phase 1 Unknown 20 enrolled Xin Wang
NaSingle-groupOpen-labelTreatment

Summary

The present study is an exploratory study. Patients who meeting the enrollment conditions for relapsed or refractory B-cell lymphoma receive a single intravenous dose of CD20-CART cells. The research with the open-label, single arm running control methods in order to initially observe the safety, tolerability, and cellular pharmacokinetics of CD20-CART cell drugs.

Timeline

Start
2018-04-04
Primary completion
2019-04-03
Completion
2020-04-03

Drugs

EvaluationDrugModalityDoseRoute
Subject CD20 CAR-T cells Cell therapy 1e+06 cells/kg Intravenous
Subject CD20 CAR-T cells Cell therapy 2e+07 cells/kg Intravenous