drugset / Trial / NCT03586427

Zelquistinel in the Treatment of Major Depressive Disorder

NCT03586427 ↗

Phase 2 Completed 251 enrolled Syndeio Biosciences, Inc
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate the efficacy at 1 day post initial oral dose of zelquistinel (AGN-241751) compared with placebo in participants with Major Depressive Disorder (MDD).

Timeline

Start
2018-06-13
Primary completion
2019-07-22
Completion
2019-08-21

Outcome

Missed primary endpoint

registry Comparison of each dose level change from baseline to placebo baseline yielded P values \>0.05 NCT03586427 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Zelquistinel Small molecule — Oral