drugset / Trial / NCT03587389
Response to Rotavirus Vaccine in Infants in Ho Chi Minh City in Vietnam
Phase 4
Completed
818 enrolled
Oxford University Clinical Research Unit, Vietnam
Children's Hospital Number 1, Ho Chi Minh City, Vietnam · collabHospital for Tropical Diseases, Ho Chi Minh City, Vietnam · collabHung Vuong Hospital · collabWellcome Sanger Institute · collab
NaSingle-groupOpen-labelPrevention
Summary
The primary objective is to measure the effect of host human genetics on the resulting immunological responses and long-term protection following rotavirus immunization of a study population of infants in Ho Chi Minh City, Vietnam. The secondary objectives are to assess the temporal immunological responses following rotavirus vaccination, and to investigate the role of maternally derived antibodies, and other factors that could potentially affect immunological responses following rotavirus vaccination. Also to assess infecting rotavirus genotypes in the vaccine failure cases.
Timeline
- Start
- 2019-03-19
- Primary completion
- 2022-06-30
- Completion
- 2022-08-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rotarix | Vaccine | 1.5 ml | Oral |