drugset / Trial / NCT03592199
Biomarker Study of Pts With Metastatic ccRCC Undergoing Sequential Therapy With 1st Line Sunitinib and 2nd Line Axitinib
NaSingle-groupOpen-labelTreatment
Summary
This is a prospective single arm phase II study to evaluate potential prognostic and/or predictive biomarkers in patients with metastatic ccRCC undergoing treatment with 1st line sunitinib on a 4/2 schedule followed by axitinib on 2nd line therapy.
Timeline
- Start
- 2017-12-11
- Primary completion
- 2019-12-11
- Completion
- 2022-12-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Axitinib | Small molecule | 5 mg | — |
| Subject | Sunitinib | Small molecule | 50 mg | — |