drugset / Trial / NCT03594552
Modulation of the Brain Excitatory/Inhibitory (E/I) Balance in Autism Spectrum Disorder (ASD)
RandomizedCrossoverDouble-blindBasic science
Summary
This study investigates the brain response to a single acute dose of Arbaclofen, the R-enantiomer of the GABA-B agonist Baclofen, compared to a single dose of placebo in healthy men with and without autism spectrum disorder.
Timeline
- Start
- 2018-02-01
- Primary completion
- 2020-03-12
- Completion
- 2020-03-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Arbaclofen | Small molecule | 15 mg | Oral |
| Subject | Arbaclofen | Small molecule | 30 mg | Oral |