drugset / Trial / NCT03598244

Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

NCT03598244

Phase 1 Active not recruiting 41 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the side effects and best dose of savolitinib in treating patients with primary central nervous system (CNS) tumors that have come back (recurrent) or does not respond to treatment (refractory). Savolitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2018-11-27
Primary completion
2025-04-14
Completion
2026-09-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Savolitinib Small molecule Oral