drugset / Trial / NCT03603405

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

NCT03603405

Phase 1/2 Recruiting 62 enrolled The Methodist Hospital Research Institute
NaSingle-groupOpen-labelTreatment

Summary

Study to assess the safety and efficacy of HSV-tk (gene therapy), valacyclovir, radiotherapy and chemotherapy in newly diagnosed glioblastoma multiforme (GBM) or anaplastic astrocytoma (AA).

Timeline

Start
2018-02-28
Primary completion
2026-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject HSV-Tk Cell therapy Other