drugset / Trial / NCT03603509
Gene Signatures of Influenza Vaccine Responses in Older Adults
Phase 4
Completed
241 enrolled
Mayo Clinic
National Institute of Allergy and Infectious Diseases (NIAID) · collab
RandomizedParallel-groupOpen-labelBasic science
Summary
The purpose of this research study is to better understand the immune response to the Adjuvanted Subunit flu vaccine (MF59) and the High Dose flu vaccine (HDFlu) in people 65 years of age and older. The research team will be studying why immune response diminishes as people get older in both men and women. The ultimate goal is to understand how flu immunity develops after vaccination. This information may lead to the development of more effective flu vaccines in the future.
Timeline
- Start
- 2018-08-27
- Primary completion
- 2019-01-02
- Completion
- 2019-01-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluad | Vaccine | — | — |
| Comparator | Influenza Virus Vaccine | Vaccine | — | — |