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drugset / Trial / NCT03609775

A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy Subjects

NCT03609775 ↗

Phase 1 Completed 22 enrolled Idorsia Pharmaceuticals Ltd.

RandomizedCrossoverQuadruple-blindOther

Summary

A study to investigate the drug-drug interactions between ACT-541468 and ethanol in healthy subjects

Timeline

Start: 2018-08-28
Primary completion: 2018-10-09
Completion: 2018-10-09

Publications

Berger B, Brooks S, Zuiker R, Richard M, Muehlan C, Dingemanse J. Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects. CNS Drugs. 2020 Dec;34(12):1253-1266. doi: 10.1007/s40263-020-00768-8. Epub 2020 Nov 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Daridorexant	Small molecule	50 mg	Oral

Indications

No indication recorded.