drugset / Trial / NCT03610282

EEG Study of IV Methylphenidate-Induced Emergence From Propofol Sedation

NCT03610282

Phase 1/2 Withdrawn Massachusetts General Hospital
RandomizedCrossoverSingle-blindBasic science

Summary

The investigators are performing this research study to find out if intravenous (IV) methylphenidate (commonly known as Ritalin) can help people recover faster from propofol sedation. The investigators also want to know how IV methylphenidate acts in the brain and whether IV methylphenidate is safe to take with an anesthetic (a drug or agent used to decrease or eliminate the feeling of pain by causing unconsciousness) without causing too many side effects. The brain's electrical activity will be studied and recorded using a machine called an electroencephalogram (EEG).

Timeline

Start
2019-11
Primary completion
2020-11
Completion
2021-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylphenidate Small molecule Intravenous
Background Propofol Small molecule

Indications

No indication recorded.