The Effect of Vitamin D3 on Postoperative Pain in Patients Undergoing Craniotomy

Summary

Vitamin D is a hormone mainly synthesized in the skin in the presence of sunlight. Like other hormones, vitamin D plays a role in a wide range of processes in the body. Some studies have shown vitamin D has anti-inflammatory effects in the body by reducing the release of pro-inflammatory cytokines and suppressing T-cell responses. Therefore, vitamin D may be effective on reduce pain by such mechanisms. In this trial patients with brain tumor under craniotomy will receive a single high dose vitamin D compared to the control group.

Timeline

Start

2017-07-30

Primary completion

2018-11-30

Completion

2018-11-30

Drugs

Indications