drugset / Trial / NCT03624244

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)

NCT03624244

Phase 2 Recruiting 40 enrolled Centre Leon Berard
RandomizedParallel-groupOpen-labelTreatment

Summary

The primary objective is to compare the progression-free survival (PFS) between aromatase inhibitors interruption and aromatase inhibitors maintenance strategies in patients with a locally advanced or metastatic Low Grade Endometrial Stromal Sarcoma (LGESS).

Timeline

Start
2019-01-23
Primary completion
2028-01
Completion
2031-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Anastrozole Other / unclassified
Subject Exemestane Small molecule
Subject Letrozole Other / unclassified