drugset / Trial / NCT03627299

Renal Transplants in Hepatitis C Negative Recipients With Nucleic Acid Positive Donors

NCT03627299

Phase 4 Completed 11 enrolled Johns Hopkins University
NaSingle-groupOpen-labelTreatment

Summary

In this study, individuals without hepatitis C infection who are on the kidney transplant waitlist will receive a kidney from a deceased donor with hepatitis C infection and will be treated for hepatitis C at the same time. Treatment will include glecaprevir 300 mg / pibrentasvir 120 mg (G-P) administered on-call to the operating room for the renal transplant procedure and continued for 4 weeks post-renal transplant.

Timeline

Start
2018-09-25
Primary completion
2019-12-19
Completion
2021-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject glecaprevir Other / unclassified 300 mg
Subject pibrentasvir Other / unclassified 120 mg Oral