drugset / Trial / NCT03634982

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

NCT03634982

Phase 1 Unknown 133 enrolled Revolution Medicines, Inc. Sanofi · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of escalating doses of RMC-4630 monotherapy in adult participants with relapsed/refractory solid tumors and to identify the recommended Phase 2 dose (RP2D).

Timeline

Start
2018-09-28
Primary completion
2023-03-31
Completion
2023-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Vociprotafib Small molecule Oral

Indications