drugset / Trial / NCT03638869
Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of REL-1017 (d-Methadone)
RandomizedParallel-groupDouble-blindBasic science
Summary
This study evaluated the safety, tolerance, and pharmacokinetics (PK) of d-methadone in a limited dose range, in multiple administrations in humans.
Timeline
- Start
- 2015-08-31
- Primary completion
- 2015-11-16
- Completion
- 2015-11-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esmethadone | Small molecule | 25 mg | Oral |
| Subject | Esmethadone | Small molecule | 50 mg | Oral |
| Subject | Esmethadone | Small molecule | 75 mg | Oral |